Broncos vs 49ers — Week 4 NFL Player Props & Matchup
Denver Broncos at San Francisco 49ers · Sunday, October 4, 2026 · Sun 4:25 PM ET · Week 4 · 2026 season · Final
Player props, odds and matchup context for Broncos at 49ers in Week 4: injury designations, 2026 offensive pace, the defense-vs-position matchup, key players — build a Broncos vs 49ers same-game parlay on ParlayBuilder.
Injury Designations (through Oct 15)
Broncos
- Pat Surtain II
- Talanoa Hufanga
- Jonah Coleman
- Levelle Bailey
- Matt Henningsen
- Michael Deiter
- Pat Bryant
- Nick Gargiulo
- Riley Moss
- Caleb Lohner
- Frank Crum
49ers
- Alfred Collins
- Andrew Farmer II
- Brett Toth
- C.J. West
- Darrick Forrest
- De'Zhaun Stribling
- Demarcus Robinson
- Jake Tonges
- Mikail Kamara
- Nate Hobbs
- Nick Martin
- Nick Zakelj
Offensive Profile (2026 season, through Week 5)
| Per game | Broncos | 49ers |
|---|---|---|
| Plays per game | 56 | 56.2 |
| Pass rate | 57.9% | 50.5% |
| Yards per game | 274 | 367.8 |
| Yards per play | 4.9 | 6.5 |
| Pass attempts | 32.4 | 28.4 |
| Rush attempts | 23.6 | 27.8 |
| Targets per game | 29.4 | 26 |
| Offensive TDs | 1.8 | 3.8 |
Ranks in parentheses are of 32 teams.
Defensive Matchup (2026 season, opponent-adjusted)
Rank 1 = toughest of 32 against that position and market, through Week 5.
Broncos defense
- vs quarterbacks: 6th in passing yards allowed (one of the tougher), 15th in passing touchdowns allowed, 11th in interceptions forced, 27th in rushing yards allowed (one of the more generous), 24th in touchdowns allowed (one of the more generous)
- vs running backs: 23rd in rushing yards allowed (one of the more generous), 20th in receptions allowed, 18th in receiving yards allowed, 13th in touchdowns allowed
- vs wide receivers: 1st in receiving yards allowed (one of the tougher), 1st in receptions allowed (one of the tougher), 5th in touchdowns allowed (one of the tougher)
- vs tight ends: 16th in receiving yards allowed, 19th in receptions allowed, 24th in touchdowns allowed (one of the more generous)
49ers defense
- vs quarterbacks: 10th in passing yards allowed (one of the tougher), 5th in passing touchdowns allowed (one of the tougher), 23rd in interceptions forced (one of the more generous), 8th in rushing yards allowed (one of the tougher), 23rd in touchdowns allowed (one of the more generous)
- vs running backs: 18th in rushing yards allowed, 32nd in receptions allowed (one of the more generous), 30th in receiving yards allowed (one of the more generous), 15th in touchdowns allowed
- vs wide receivers: 10th in receiving yards allowed (one of the tougher), 13th in receptions allowed, 15th in touchdowns allowed
- vs tight ends: 7th in receiving yards allowed (one of the tougher), 9th in receptions allowed (one of the tougher), 2nd in touchdowns allowed (one of the tougher)
Key Players
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