49ers vs Seahawks — Week 5 NFL Player Props & Matchup
San Francisco 49ers at Seattle Seahawks · Sunday, October 11, 2026 · Sun 4:25 PM ET · Week 5 · 2026 season · Final
Player props, odds and matchup context for 49ers at Seahawks in Week 5: injury designations, 2026 offensive pace, the defense-vs-position matchup, key players — build a 49ers vs Seahawks same-game parlay on ParlayBuilder.
Injury Designations (through Oct 15)
49ers
- Alfred Collins
- Andrew Farmer II
- Brett Toth
- C.J. West
- Darrick Forrest
- De'Zhaun Stribling
- Demarcus Robinson
- Jake Tonges
- Mikail Kamara
- Nate Hobbs
- Nick Martin
- Nick Zakelj
Seahawks
- Chazz Surratt
- Drake Thomas
- Anthony Bradford
- Bud Clark
- Jadarian Price
- Jake Bobo
- Julian Neal
- Mason Richman
- Robbie Ouzts
- Zach Charbonnet
Offensive Profile (2026 season, through Week 5)
| Per game | 49ers | Seahawks |
|---|---|---|
| Plays per game | 56.2 | 57.2 |
| Pass rate | 50.5% | 51.4% |
| Yards per game | 367.8 | 344.2 |
| Yards per play | 6.5 | 6 |
| Pass attempts | 28.4 | 29.4 |
| Rush attempts | 27.8 | 27.8 |
| Targets per game | 26 | 27.8 |
| Offensive TDs | 3.8 | 3 |
Ranks in parentheses are of 32 teams.
Defensive Matchup (2026 season, opponent-adjusted)
Rank 1 = toughest of 32 against that position and market, through Week 5.
49ers defense
- vs quarterbacks: 10th in passing yards allowed (one of the tougher), 5th in passing touchdowns allowed (one of the tougher), 23rd in interceptions forced (one of the more generous), 8th in rushing yards allowed (one of the tougher), 23rd in touchdowns allowed (one of the more generous)
- vs running backs: 18th in rushing yards allowed, 32nd in receptions allowed (one of the more generous), 30th in receiving yards allowed (one of the more generous), 15th in touchdowns allowed
- vs wide receivers: 10th in receiving yards allowed (one of the tougher), 13th in receptions allowed, 15th in touchdowns allowed
- vs tight ends: 7th in receiving yards allowed (one of the tougher), 9th in receptions allowed (one of the tougher), 2nd in touchdowns allowed (one of the tougher)
Seahawks defense
- vs quarterbacks: 1st in passing yards allowed (one of the tougher), 23rd in passing touchdowns allowed (one of the more generous), 3rd in interceptions forced (one of the tougher), 5th in rushing yards allowed (one of the tougher), 6th in touchdowns allowed (one of the tougher)
- vs running backs: 14th in rushing yards allowed, 30th in receptions allowed (one of the more generous), 25th in receiving yards allowed (one of the more generous), 23rd in touchdowns allowed (one of the more generous)
- vs wide receivers: 5th in receiving yards allowed (one of the tougher), 7th in receptions allowed (one of the tougher), 17th in touchdowns allowed
- vs tight ends: 3rd in receiving yards allowed (one of the tougher), 12th in receptions allowed, 13th in touchdowns allowed
Key Players
49ers
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