Bills vs Rams — Week 5 NFL Player Props & Matchup

Buffalo Bills at Los Angeles Rams · Monday, October 12, 2026 · Mon 8:15 PM ET · Week 5 · 2026 season · Final

Player props, odds and matchup context for Bills at Rams in Week 5: injury designations, 2026 offensive pace, the defense-vs-position matchup, key players — build a Bills vs Rams same-game parlay on ParlayBuilder.

Injury Designations (through Oct 15)

Bills

  • Jordan Hancock CB · IR
  • Tyrell Shavers WR · PUP-R
  • Dorian Strong CB · NFI-R
  • DJ Moore WR · Questionable
  • Dee Alford CB · Questionable
  • Ed Oliver DT · Questionable
  • Joshua Palmer WR · Questionable
  • Spencer Brown OT · Questionable
  • T.J. Sanders DT · Questionable
  • Ty Johnson RB · Questionable
  • Zane Durant DT · IR-R

Rams

  • Daniel Rickert DE · IR
  • Eddie Walls III LB · IR
  • Keir Thomas II LB · IR
  • Matthew Caldwell QB · IR
  • Myles Garrett DE · IR
  • Ronnie Rivers RB · IR
  • Terrance Ferguson TE · IR
  • Alaric Jackson OT · Reserve-Sus
  • Colby Parkinson TE · Questionable
  • Davis Allen TE · Questionable
  • Josh Wallace CB · Questionable
  • Nate Landman LB · Questionable

Offensive Profile (2026 season, through Week 5)

Per gameBillsRams
Plays per game57 (23)69.4 (2)
Pass rate48.4% (29)63.1% (5)
Yards per game407.8433.8
Yards per play7.26.3
Pass attempts27.6 (29)43.8 (1)
Rush attempts29.4 (7)25.6 (20)
Targets per game26 (28)42 (1)
Offensive TDs4 (1)3 (8)

Ranks in parentheses are of 32 teams.

Defensive Matchup (2026 season, opponent-adjusted)

Rank 1 = toughest of 32 against that position and market, through Week 5.

Bills defense

  • vs quarterbacks: 28th in passing yards allowed (one of the more generous), 32nd in passing touchdowns allowed (one of the more generous), 31st in interceptions forced (one of the more generous), 21st in rushing yards allowed, 11th in touchdowns allowed
  • vs running backs: 13th in rushing yards allowed, 23rd in receptions allowed (one of the more generous), 24th in receiving yards allowed (one of the more generous), 28th in touchdowns allowed (one of the more generous)
  • vs wide receivers: 26th in receiving yards allowed (one of the more generous), 32nd in receptions allowed (one of the more generous), 31st in touchdowns allowed (one of the more generous)
  • vs tight ends: 14th in receiving yards allowed, 15th in receptions allowed, 12th in touchdowns allowed

Rams defense

  • vs quarterbacks: 2nd in passing yards allowed (one of the tougher), 17th in passing touchdowns allowed, 10th in interceptions forced (one of the tougher), 31st in rushing yards allowed (one of the more generous), 15th in touchdowns allowed
  • vs running backs: 20th in rushing yards allowed, 29th in receptions allowed (one of the more generous), 31st in receiving yards allowed (one of the more generous), 8th in touchdowns allowed (one of the tougher)
  • vs wide receivers: 6th in receiving yards allowed (one of the tougher), 6th in receptions allowed (one of the tougher), 28th in touchdowns allowed (one of the more generous)
  • vs tight ends: 1st in receiving yards allowed (one of the tougher), 2nd in receptions allowed (one of the tougher), 6th in touchdowns allowed (one of the tougher)

Full defense-vs-position rankings →

Key Players

Bills

  • Josh Allen QB · 1249 pass yds, 7 TD, 4 INT (2026, 5 games)
  • James Cook RB · 532 rush yds, 5 TD, 7 rec (2026, 5 games)
  • Ty Johnson RB · 200 rush yds, 3 TD, 24 rec (2025, 17 games)
  • Greg Dortch WR · 29 rec, 206 yds, 3 TD (2025, 12 games)
  • Joshua Palmer WR · 22 rec, 303 yds, 0 TD (2025, 12 games)
  • Khalil Shakir WR · 18 rec, 256 yds, 0 TD (2026, 5 games)
  • Dalton Kincaid TE · 16 rec, 277 yds, 1 TD (2026, 5 games)

Rams

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