Dolphins vs 49ers — Week 2 NFL Player Props & Matchup

Miami Dolphins at San Francisco 49ers · Sunday, September 20, 2026 · Sun 4:25 PM ET · Week 2 · 2026 season

Player props, odds and matchup context for Dolphins at 49ers in Week 2: injury designations, 2025 offensive pace, the defense-vs-position matchup, key players — build a Dolphins vs 49ers same-game parlay on ParlayBuilder.

Injury Designations (through Sep 8)

Dolphins

  • Ben Sims TE · IR
  • Cole Turner TE · IR
  • Rene Konga DT · IR
  • Darrell Baker Jr. CB · PUP-R
  • Storm Duck CB · PUP-R
  • Kenneth Grant DT · IR-R
  • Trey Moore LB · IR-R

49ers

  • Andrew Farmer II DE · IR
  • Brett Toth C · IR
  • Darrick Forrest S · IR
  • Mikail Kamara DE · IR
  • Nate Hobbs CB · IR
  • Nick Martin LB · IR
  • Nick Zakelj OT · IR
  • Ricky Pearsall WR · IR
  • Sam Okuayinonu DT · IR
  • Brandon Aiyuk WR · Reserve-DNR
  • Isaac Guerendo RB · PUP-R
  • Mykel Williams DE · PUP-R

Offensive Profile (2025 season, through Week 18)

Per gameDolphins49ers
Plays per game53.6 (30)61.9 (7)
Pass rate52.6% (23)54.5% (16)
Yards per game315.8361.1
Yards per play5.95.8
Pass attempts28.2 (30)33.8 (11)
Rush attempts25.4 (24)28.2 (9)
Targets per game26.6 (29)30.6 (17)
Offensive TDs2.2 (21)2.8 (8)

Ranks in parentheses are of 32 teams.

Defensive Matchup (2025 season, opponent-adjusted)

Rank 1 = toughest of 32 against that position and market, through Week 18.

Dolphins defense

  • vs quarterbacks: 24th in passing yards allowed (one of the more generous), 25th in passing touchdowns allowed (one of the more generous), 17th in interceptions forced, 11th in rushing yards allowed, 8th in touchdowns allowed (one of the tougher)
  • vs running backs: 23rd in rushing yards allowed (one of the more generous), 25th in receptions allowed (one of the more generous), 16th in receiving yards allowed, 31st in touchdowns allowed (one of the more generous)
  • vs wide receivers: 24th in receiving yards allowed (one of the more generous), 22nd in receptions allowed (one of the more generous), 23rd in touchdowns allowed (one of the more generous)
  • vs tight ends: 27th in receiving yards allowed (one of the more generous), 32nd in receptions allowed (one of the more generous), 27th in touchdowns allowed (one of the more generous)

49ers defense

  • vs quarterbacks: 23rd in passing yards allowed (one of the more generous), 22nd in passing touchdowns allowed (one of the more generous), 25th in interceptions forced (one of the more generous), 9th in rushing yards allowed (one of the tougher), 5th in touchdowns allowed (one of the tougher)
  • vs running backs: 14th in rushing yards allowed, 32nd in receptions allowed (one of the more generous), 27th in receiving yards allowed (one of the more generous), 19th in touchdowns allowed
  • vs wide receivers: 21st in receiving yards allowed, 25th in receptions allowed (one of the more generous), 13th in touchdowns allowed
  • vs tight ends: 20th in receiving yards allowed, 24th in receptions allowed (one of the more generous), 23rd in touchdowns allowed (one of the more generous)

Full defense-vs-position rankings →

Key Players

Dolphins

49ers

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