Patriots vs Bills — Week 4 NFL Player Props & Matchup
New England Patriots at Buffalo Bills · Sunday, October 4, 2026 · Sun 1:00 PM ET · Week 4 · 2026 season · Final
Player props, odds and matchup context for Patriots at Bills in Week 4: injury designations, 2026 offensive pace, the defense-vs-position matchup, key players — build a Patriots vs Bills same-game parlay on ParlayBuilder.
Injury Designations (through Oct 15)
Patriots
- Bryce Baringer
- Dell Pettus
- Greg Van Roten
- Jeremiah Webb
- Julian Hill
- Khalil Jacobs
- Mack Hollins
- Mike Onwenu
- Myles Montgomery
- Quintayvious Hutchins
- Reggie Gilliam
- Harold Landry III
Bills
- Jordan Hancock
- Tyrell Shavers
- Dorian Strong
- DJ Moore
- Dee Alford
- Ed Oliver
- Joshua Palmer
- Spencer Brown
- T.J. Sanders
- Ty Johnson
- Zane Durant
Offensive Profile (2026 season, through Week 5)
| Per game | Patriots | Bills |
|---|---|---|
| Plays per game | 61.6 | 57 |
| Pass rate | 51% | 48.4% |
| Yards per game | 382 | 407.8 |
| Yards per play | 6.2 | 7.2 |
| Pass attempts | 31.4 | 27.6 |
| Rush attempts | 30.2 | 29.4 |
| Targets per game | 29.4 | 26 |
| Offensive TDs | 2.4 | 4 |
Ranks in parentheses are of 32 teams.
Defensive Matchup (2026 season, opponent-adjusted)
Rank 1 = toughest of 32 against that position and market, through Week 5.
Patriots defense
- vs quarterbacks: 9th in passing yards allowed (one of the tougher), 2nd in passing touchdowns allowed (one of the tougher), 25th in interceptions forced (one of the more generous), 12th in rushing yards allowed, 9th in touchdowns allowed (one of the tougher)
- vs running backs: 3rd in rushing yards allowed (one of the tougher), 24th in receptions allowed (one of the more generous), 14th in receiving yards allowed, 21st in touchdowns allowed
- vs wide receivers: 13th in receiving yards allowed, 24th in receptions allowed (one of the more generous), 9th in touchdowns allowed (one of the tougher)
- vs tight ends: 6th in receiving yards allowed (one of the tougher), 6th in receptions allowed (one of the tougher), 5th in touchdowns allowed (one of the tougher)
Bills defense
- vs quarterbacks: 28th in passing yards allowed (one of the more generous), 32nd in passing touchdowns allowed (one of the more generous), 31st in interceptions forced (one of the more generous), 21st in rushing yards allowed, 11th in touchdowns allowed
- vs running backs: 13th in rushing yards allowed, 23rd in receptions allowed (one of the more generous), 24th in receiving yards allowed (one of the more generous), 28th in touchdowns allowed (one of the more generous)
- vs wide receivers: 26th in receiving yards allowed (one of the more generous), 32nd in receptions allowed (one of the more generous), 31st in touchdowns allowed (one of the more generous)
- vs tight ends: 14th in receiving yards allowed, 15th in receptions allowed, 12th in touchdowns allowed
Key Players
Patriots
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