Colts vs Chiefs — Week 2 NFL Player Props & Matchup
Indianapolis Colts at Kansas City Chiefs · Sunday, September 20, 2026 · Sun 8:20 PM ET · Week 2 · 2026 season
Player props, odds and matchup context for Colts at Chiefs in Week 2: injury designations, 2025 offensive pace, the defense-vs-position matchup, key players — build a Colts vs Chiefs same-game parlay on ParlayBuilder.
Injury Designations (through Sep 8)
Colts
- Cameron Mitchell
- Carson Towt
- Coleman Owen
- D.J. Montgomery
- Cam Taylor-Britt
- Will Mallory
Chiefs
- Ethan Downs
- Jeff Caldwell
- Jimmy Holiday
- John Michael Gyllenborg
- Matt Waletzko
- Omarr Norman-Lott
- Patrick Mahomes
Offensive Profile (2025 season, through Week 18)
| Per game | Colts | Chiefs |
|---|---|---|
| Plays per game | 58.1 | 59.6 |
| Pass rate | 55.3% | 57.6% |
| Yards per game | 357.2 | 338.1 |
| Yards per play | 6.2 | 5.7 |
| Pass attempts | 32.1 | 34.4 |
| Rush attempts | 25.9 | 25.2 |
| Targets per game | 30.7 | 32.3 |
| Offensive TDs | 3.1 | 2.2 |
Ranks in parentheses are of 32 teams.
Defensive Matchup (2025 season, opponent-adjusted)
Rank 1 = toughest of 32 against that position and market, through Week 18.
Colts defense
- vs quarterbacks: 29th in passing yards allowed (one of the more generous), 11th in passing touchdowns allowed, 12th in interceptions forced, 13th in rushing yards allowed, 27th in touchdowns allowed (one of the more generous)
- vs running backs: 13th in rushing yards allowed, 12th in receptions allowed, 3rd in receiving yards allowed (one of the tougher), 16th in touchdowns allowed
- vs wide receivers: 29th in receiving yards allowed (one of the more generous), 31st in receptions allowed (one of the more generous), 14th in touchdowns allowed
- vs tight ends: 30th in receiving yards allowed (one of the more generous), 21st in receptions allowed, 13th in touchdowns allowed
Chiefs defense
- vs quarterbacks: 10th in passing yards allowed (one of the tougher), 5th in passing touchdowns allowed (one of the tougher), 23rd in interceptions forced (one of the more generous), 8th in rushing yards allowed (one of the tougher), 23rd in touchdowns allowed (one of the more generous)
- vs running backs: 12th in rushing yards allowed, 13th in receptions allowed, 15th in receiving yards allowed, 13th in touchdowns allowed
- vs wide receivers: 8th in receiving yards allowed (one of the tougher), 12th in receptions allowed, 4th in touchdowns allowed (one of the tougher)
- vs tight ends: 10th in receiving yards allowed (one of the tougher), 8th in receptions allowed (one of the tougher), 8th in touchdowns allowed (one of the tougher)
Key Players
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